Detalhe da pesquisa
1.
Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time.
Cell
; 177(4): 896-909.e20, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31030999
2.
Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.
Annu Rev Pharmacol Toxicol
; 58: 65-82, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29029591
3.
Determination of the safety and efficacy of therapeutic neutralization of tumor necrosis factor-α (TNF-α) using AZD9773, an anti-TNF-α immune Fab, in murine CLP sepsis.
Inflamm Res
; 63(2): 149-60, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24240228
4.
Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6.
Arthritis Rheum
; 64(7): 2289-99, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22294415
5.
The evolving role of investigative toxicology in the pharmaceutical industry.
Nat Rev Drug Discov
; 22(4): 317-335, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36781957
6.
Using human genetics to improve safety assessment of therapeutics.
Nat Rev Drug Discov
; 22(2): 145-162, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261593
7.
Matrix metalloproteinase 17 is necessary for cartilage aggrecan degradation in an inflammatory environment.
Ann Rheum Dis
; 70(4): 683-9, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21216815
8.
Modulation of integrin α4ß1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration.
Cell Biol Int
; 35(10): 1043-53, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21332445
9.
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Nat Commun
; 12(1): 6035, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34654800
10.
Novel inhibitors of the alphavbeta3 integrin--lead identification strategy.
Bioorg Med Chem Lett
; 19(16): 4832-5, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19574045
11.
Optimizing drug discovery by Investigative Toxicology: Current and future trends.
ALTEX
; 36(2): 289-313, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570669
12.
Transcriptional profiling of the LPS induced NF-kappaB response in macrophages.
BMC Immunol
; 8: 1, 2007 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17222336
13.
Publisher Correction: Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Nat Commun
; 12(1): 6988, 2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819501
14.
Characterisation of cell-penetrating peptide-mediated peptide delivery.
Br J Pharmacol
; 145(8): 1093-102, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15937518
15.
Quantification of Low-Level Drug Effects Using Real-Time, in vitro Measurement of Oxygen Consumption Rate.
Toxicol Sci
; 148(2): 594-602, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396153
16.
Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα.
Biosci Rep
; 33(4)2013 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863106
17.
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.
Arthritis Rheum
; 60(2): 501-12, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19180479
18.
Gene expression profiles at different stages of collagen-induced arthritis.
Autoimmunity
; 41(7): 512-21, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18608173
19.
A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation.
J Cell Sci
; 118(Pt 2): 291-300, 2005 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15615773
20.
Expression and purification of biologically active IGF-binding proteins using the LCR/Mel expression system.
Protein Expr Purif
; 27(1): 1-11, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509978